N-Cadherin Antikörper (AA 690-770)

Produktnummer ABIN7215970

Der Kaninchen Polyklonal anti-N-Cadherin Antikörper wird verwendet zum Nachweis von N-Cadherin in Proben von Human, Maus und Ratte. Er wurde validiert für WB, IHC, IF und ELISA.

Kurzübersicht für N-Cadherin Antikörper (AA 690-770) (ABIN7215970)

Target: N-Cadherin (CDH2) (Cadherin 2 (CDH2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser N-Cadherin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA

Produktdetails anti-N-Cadherin Antikörper

Bindungsspezifität: AA 690-770

Verwendungszweck: Rabbit Anti-N-cadherin Polyclonal Antibody

Spezifität: N-cadherin Polyclonal Antibody detects endogenous levels of N-cadherin protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the C-terminal region of human N-cadherin at AA range: 690-770

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,IF 1:200-1:1000,ELISA 1:10000,Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu N-Cadherin

Target: N-Cadherin (CDH2) (Cadherin 2 (CDH2))

Andere Bezeichnung: N-cadherin

Hintergrund: CDH2, CDHN, NCAD, Cadherin-2, CDw325, Neural cadherin, N-cadherin, CD antigen CD325CDH2 encodes a classical cadherin and member of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein is proteolytically processed to generate a calcium-dependent cell adhesion molecule and glycoprotein. Cadherin-2 plays a role in the establishment of left-right asymmetry, development of the nervous system and the formation of cartilage and bone.

Molekulargewicht: 100-140kD

Gen-ID: 1000

UniProt: P19022

Pathways: Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Synaptic Membrane