Septin 5 Antikörper (AA 21-120) (Cy5.5)

Produktnummer ABIN889724

Der Kaninchen Polyklonal Anti-Septin 5-Antikörper wurde für WB, IF (cc) und IF (p) validiert. Er ist geeignet, Septin 5 in Proben von Human und Ratte zu detektieren.

Kurzübersicht für Septin 5 Antikörper (AA 21-120) (Cy5.5) (ABIN889724)

Target: Septin 5 (SEPT5)

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Septin 5 Antikörper ist konjugiert mit Cy5.5

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-Septin 5 Antikörper (Cy5.5)

Bindungsspezifität: AA 21-120

Kreuzreaktivität: Human, Ratte

Homologie: Mouse,Dog,Cow,Pig,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CDCREL/SEPT5

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu Septin 5

Target: Septin 5 (SEPT5)

Andere Bezeichnung: Septin5

Hintergrund:

Synonyms: 5 Sep, CDCrel 1, CDCREL, CDCrel-1, CDCREL1, Cell division control related protein 1, Cell division control-related protein 1, H5 antibody HCDCREL 1, Peanut like 1, Peanut like 1 homolog, Peanut like protein 1, Peanut-like protein 1, Platelet glycoprotein Ib beta chain, PNUTL1, SEPT5, SEPT-5, SEPT 5, SEPT5_HUMAN, Septin 5, Septin5, Septin-5.

Background: This gene is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is mapped to 22q11, the region frequently deleted in DiGeorge and velocardiofacial syndromes. A translocation involving the MLL gene and this gene has also been reported in patients with acute myeloid leukemia. Alternative splicing results in multiple transcript variants. The presence of a non-consensus polyA signal (AACAAT) in this gene also results in read-through transcription into the downstream neighboring gene (GP1BB, platelet glycoprotein Ib), whereby larger, non-coding transcripts are produced. [provided by RefSeq, Dec 2010].

Gen-ID: 5413

UniProt: Q99719

Pathways: Synaptic Vesicle Exocytosis