CD44v7 Antikörper (AA 218-230) (Alexa Fluor 647)
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- Target Alle CD44v7 Produkte
- CD44v7
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Bindungsspezifität
- AA 218-230
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CD44v7 Antikörper ist konjugiert mit Alexa Fluor 647
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Applikation
- Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Spezifität
- This antibody will detect isoform 7 exclusively.
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human CD44v7
- Isotyp
- IgG
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anti-CD44v7 (AA 201-300) antibody
Reaktivität: Human, Maus WB, IHC (p), ELISA Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- IF(IHC-P) 1:50-200
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Store at 4°C
- Haltbarkeit
- 12 months
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- Target
- CD44v7
- Abstract
- CD44v7 Produkte
- Hintergrund
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Receptor for hyaluronic acid (HA). Mediates cell-cell and cell-matrix interactions through its affinity for HA, and possibly also through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases (MMPs). Adhesion with HA plays an important role in cell migration, tumor growth and progression. In cancer cells, may play an important role in invadopodia formation. Also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. Altered expression or dysfunction causes numerous pathogenic phenotypes. Great protein heterogeneity due to numerous alternative splicing and post-translational modification events.
Subcellular location: Extracellular
Synonyms: IN, LHR, MC56, MDU2, MDU3, MIC4, Pgp1, CDW44, CSPG8, HCELL, HUTCH-I, ECMR-III, CD44 antigen, Epican, Extracellular matrix receptor III, GP90 lymphocyte homing/adhesion receptor, Heparan sulfate proteoglycan, Hermes antigen, Hyaluronate receptor, Phagocytic glycoprotein 1, PGP-1, Phagocytic glycoprotein I, PGP-I, CD44
- Gen-ID
- 960
- UniProt
- P16070
