Cadherin 5 Antikörper (AA 601-700) (AbBy Fluor® 488)

Produktnummer ABIN888741

Dieses Anti-Cadherin 5-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Cadherin 5 in WB, FACS, IF (p) und IF (cc). Geeignet für Human, Maus und Ratte.

Kurzübersicht für Cadherin 5 Antikörper (AA 601-700) (AbBy Fluor® 488) (ABIN888741)

Target: Cadherin 5 (CDH5)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Cadherin 5 Antikörper ist konjugiert mit AbBy Fluor® 488

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Produktdetails anti-Cadherin 5 Antikörper (AbBy Fluor® 488)

Bindungsspezifität: AA 601-700

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse vascular endothelial cadherin

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu Cadherin 5

Target: Cadherin 5 (CDH5)

Andere Bezeichnung: VE Cadherin

Hintergrund:

Synonyms: 7B4, Vec, VECD, Cd144, VEcad, VE-Cad, AA48225, Cadherin-5, Vascular endothelial cadherin, VE-cadherin, Cdh5

Background: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells, cadherins may thus contribute to the sorting of heterogeneous cell types. This cadherin may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. Acts in concert with KRIT1 to establish and maintain correct endothelial cell polarity and vascular lumen. These effects are mediated by recruitment and activation of the Par polarity complex and RAP1B. Required for activation of PRKCZ and for localization of phosphorylated PRKCZ, PARD3, TIAM1 and RAP1B to the cell junction.

Gen-ID: 12562

UniProt: P55284

Pathways: Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2