Endoglin Antikörper (AA 601-658) (AbBy Fluor® 350)
Kurzübersicht für Endoglin Antikörper (AA 601-658) (AbBy Fluor® 350) (ABIN888674)
Target
Alle Endoglin (ENG) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- AA 601-658
-
Homologie
- Mouse,Dog,Cow,Pig,Horse,Chicken
-
Aufreinigung
- Purified by Protein A.
-
Immunogen
- KLH conjugated synthetic peptide derived from human CD105
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
-
FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- 1 μg/μL
-
Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
-
Konservierungsmittel
- ProClin
-
Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
Lagerung
- -20 °C/-80 °C
-
Informationen zur Lagerung
- Store at -20°C, for long storage, store at -80°C. Avoid multiple freeze-thaw cycles
-
Haltbarkeit
- 12 months
-
-
- Endoglin (ENG)
-
Andere Bezeichnung
- CD105
-
Hintergrund
-
Major glycoprotein of vascular endothelium. Involved in the regulation of angiogenesis. May play a critical role in the binding of endothelial cells to integrins and/or other RGD receptors. Acts as TGF-beta coreceptor and is involved in the TGF-beta/BMP signaling cascade. Required for GDF2/BMP9 signaling through SMAD1 in endothelial cells and modulates TGF-beta1 signaling through SMAD3.
Subcellular location: Cell membrane
Synonyms: END, HHT1, ORW1, Endoglin, CD15, ENG
-
Gen-ID
- 2022
-
UniProt
- P17813
Target
-