CARD8 Antikörper (AA 221-320) (Cy5)

Produktnummer ABIN886510

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch CARD8 in WB, IF (cc) und IF (p). Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für CARD8 Antikörper (AA 221-320) (Cy5) (ABIN886510)

Target: CARD8 (Caspase Recruitment Domain Family, Member 8 (CARD8))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CARD8 Antikörper ist konjugiert mit Cy5

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-CARD8 Antikörper (Cy5)

Bindungsspezifität: AA 221-320

Homologie: Human

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CARD8

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu CARD8

Target: CARD8 (Caspase Recruitment Domain Family, Member 8 (CARD8))

Andere Bezeichnung: CARD8

Hintergrund:

Synonyms: Apoptotic protein NDPP 1, Apoptotic protein NDPP1, CARD 8, CARD inhibitor of NF kappa B activating ligand, CARD inhibitor of NF kappaB activating ligand, CARD inhibitor of NF kappaB activating ligands, CARD-inhibitor of NF-kappa-B-activating ligand, CARD8, CARD8_HUMAN, CARDINAL, Caspase recruitment domain containing protein 8, Caspase recruitment domain family member 8, Caspase recruitment domain protein 8, Caspase recruitment domain-containing protein 8, DACAR, NDPP 1, NDPP1, TUCAN, Tumor up regulated CARD containing antagonist of CASP9, Tumor up regulated CARD containing antagonist of caspase 9, Tumor up-regulated CARD-containing antagonist of CASP9, Tumor upregulated CARD containing antagonist of CASP9.

Background: Inhibits NF-kappa-B activation. May participate in a regulatory mechanism that coordinates cellular responses controlled by NF-kappa-B transcription factor. May be a component of the inflammasome, a protein complex which also includes PYCARD, NALP2 and CASP1 and whose function would be the activation of proinflammatory caspases.

Gen-ID: 22900

Pathways: Positive Regulation of Endopeptidase Activity