Cortactin Antikörper (pThr466) (AbBy Fluor® 555)
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- Target Alle Cortactin (CTTN) Antikörper anzeigen
- Cortactin (CTTN)
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Bindungsspezifität
- pThr466
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Cortactin Antikörper ist konjugiert mit AbBy Fluor® 555
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Applikation
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Kreuzreaktivität
- Human
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic phosphopeptide derived from human Cortactin around the phosphorylation site of Tyr466(YAp-TEA)
- Isotyp
- IgG
- Top Product
- Discover our top product CTTN Primärantikörper
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anti-Cortactin (CTTN) (N-Term) antibody
KO Validated CTTN Reaktivität: Human WB, IF, IHC (p), ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Cortactin (CTTN) (AA 214-513) antibodyCTTN Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-Cortactin (CTTN) antibodyCTTN Reaktivität: Human WB, IHC, IF, IP Wirt: Kaninchen Monoclonal unconjugated
anti-Cortactin (CTTN) (AA 341-450) antibodyCTTN Reaktivität: Human WB, ELISA, PLA Wirt: Maus Monoclonal 2B5 unconjugated
anti-Cortactin (CTTN) antibodyCTTN Reaktivität: Human WB, IHC, ELISA Wirt: Maus Monoclonal 4C6 unconjugated
anti-Cortactin (CTTN) (pTyr466) antibodyCTTN Reaktivität: Human, Maus, Ratte WB, IHC, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Cortactin (CTTN) (AA 1-509) antibodyCTTN Reaktivität: Maus WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Cortactin (CTTN) (AA 1-509) antibodyCTTN Reaktivität: Ratte WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Cortactin (CTTN) (AA 273-302) antibodyCTTN Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB33698 unconjugated
anti-Cortactin (CTTN) (pTyr421) antibodyCTTN Reaktivität: Human, Maus, Ratte WB, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- Cortactin (CTTN)
- Andere Bezeichnung
- Cortactin (CTTN Produkte)
- Hintergrund
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Synonyms: Amplaxin, CTTN, EMS 1, EMS1, Mammary tumor and squamous cell carcinoma associated, Oncogene EMS1, p80/85 src substrate, Src substrate cortactin, SRC8_HUMAN.
Background: Cortactin is an 80/85 kDa cytoskeleton protein that facilitates assembly of cortical actin. Cortactin is widely expressed in most adherent cells and is a prominent substrate of protein tyrosine kinase Src in vivo and in vitro. The protein sequence of cortactin contains multiple amino terminal tandem repeats of a unique 37 amino acid sequence, which associates with actin, and a Src homology 3 (SH3) domain at the carboxyl terminus. Between the repeat and the SH3 domain, there is an alpha helical structure followed by a proline rich region. Between the proline rich region and the SH3 domain, there are a series of Src phosphorylation sites (Tyr421, Tyr470, and Tyr486). In vitro, cortactin binds to and cross links F actin into meshworks.
- Gen-ID
- 2017
- Pathways
- MAPK Signalweg
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