DUSP1 Antikörper (pSer359) (AbBy Fluor® 555)

Produktnummer ABIN875712

Dieses Anti-DUSP1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von DUSP1 in WB, IF (cc) und IF (p). Geeignet für Human.

Kurzübersicht für DUSP1 Antikörper (pSer359) (AbBy Fluor® 555) (ABIN875712)

Target: DUSP1 (Dual Specificity Phosphatase 1 (DUSP1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DUSP1 Antikörper ist konjugiert mit AbBy Fluor® 555

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-DUSP1 Antikörper (AbBy Fluor® 555)

Bindungsspezifität: pSer359

Homologie: Human,Rat,Dog,Cow,Pig,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human MKP1 around the phosphorylation site of Ser359

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu DUSP1

Target: DUSP1 (Dual Specificity Phosphatase 1 (DUSP1))

Andere Bezeichnung: MKP1

Hintergrund:

Synonyms: Mitogen activated protein kinase phosphatase 1, CL 100, CL100, Dual Specicity Phosphatase 1, Dual specicity protein phosphatase 1, Dual specicity protein phosphatase hVH1, DUSP 1, EC 3.1.3.16, EC 3.1.3.48, HVH 1, HVH1, MAP kinase phosphatase 1, MKP 1, MKP1, MKP-1, Protein tyrosine phosphatase CL100, PTPN 10, PTPN10, Serine/threonine specic protein phosphatase, VH 1, VH1, 3ch134, Mkp1, Ptpn16.

Background: The expression of DUSP1 gene is induced in human skin fibroblasts by oxidative/heat stress and growth factors. It specifies a protein with structural features similar to members of the non-receptor-type protein-tyrosine phosphatase family, and which has significant amino-acid sequence similarity to a Tyr/Ser-protein phosphatase encoded by the late gene H1 of vaccinia virus. The bacterially expressed and purified DUSP1 protein has intrinsic phosphatase activity, and specifically inactivates mitogen-activated protein (MAP) kinase in vitro by the concomitant dephosphorylation of both its phosphothreonine and phosphotyrosine residues.

Gen-ID: 1843