tau Antikörper (pSer356) (AbBy Fluor® 350)

Produktnummer ABIN875709

Dieses Anti-tau-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von tau in IF (p) und IF (cc). Geeignet für Maus und Ratte.

Kurzübersicht für tau Antikörper (pSer356) (AbBy Fluor® 350) (ABIN875709)

Target: tau (tau Protein)

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser tau Antikörper ist konjugiert mit AbBy Fluor® 350

Applikation: Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Produktdetails anti-tau Antikörper (AbBy Fluor® 350)

Bindungsspezifität: pSer356

Kreuzreaktivität: Maus, Ratte

Homologie: Human,Dog,Cow,Horse,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human Tau protein(Ser356) around the phosphorylation site of Ser356 [IG(p-S)LD]

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu tau

Target: tau (tau Protein)

Hintergrund:

Synonyms: MAPTphospho S356, MAPT, Microtuble-associted protein Tau, AI413597, AW045860, DDPAC, Disinhibition dementia parkinsonism amyotrophy complex, FLJ31424, FTDP 17, FTDP17, G Protein beta 1 gamma 2 subunit interacting factor 1, G protein beta1/gamma2 subunit interacting factor 1, MAPTL, MGC134287, MGC138549, MGC156663, Microtubule associated protein tau isoform 4, MSTD, Mtapt, MTBT1, MTBT2, Neurofibrillary tangle protein, Paired helical filament tau, PHF tau, PHF-tau, PPND, pTau, RNPTAU, Tauopathy and respiratory failure, included, TAU_HUMAN.

Background: Tau proteins are important Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization. Tau proteins subcellular located in the axons of neurons, in the cytoso l and in association with plasma membrane components. It expressed in neurons. PNS-tau is expressed in the peripheral nervous system while the others are expressed in the central nervous system.

Gen-ID: 4137