PPM1F Antikörper (AA 325-425)
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- Target Alle PPM1F Antikörper anzeigen
- PPM1F (Protein Phosphatase 1F (PP2C Domain Containing) (PPM1F))
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Bindungsspezifität
- AA 325-425
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser PPM1F Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Homologie
- Human,Mouse,Rat,Dog,Cow,Pig,Horse
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human PPM1F
- Isotyp
- IgG
- Top Product
- Discover our top product PPM1F Primärantikörper
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- Applikationshinweise
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- PPM1F (Protein Phosphatase 1F (PP2C Domain Containing) (PPM1F))
- Andere Bezeichnung
- PPM1F (PPM1F Produkte)
- Synonyme
- 1110021B16Rik antikoerper, 4933427B07Rik antikoerper, CaMKPase antikoerper, Popx2 antikoerper, mKIAA0015 antikoerper, CAMKP antikoerper, FEM-2 antikoerper, POPX2 antikoerper, hFEM-2 antikoerper, protein phosphatase, Mg2+/Mn2+ dependent 1F antikoerper, protein phosphatase 1F (PP2C domain containing) antikoerper, protein phosphatase, Mg2+/Mn2+ dependent, 1F antikoerper, PPM1F antikoerper, Ppm1f antikoerper
- Hintergrund
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Synonyms: Ca2+/calmodulin-dependent protein kinase phosphatase, CaM-kinase phosphatase,CaMKPase, hFEM-2, KIAA0015, Partner of PIX 2, POPX2, Protein phosphatase 1F, PPM1F_HUMAN.
Background: The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase can interact with Rho guanine nucleotide exchange factors (PIX), and thus block the effects of p21-activated kinase 1 (PAK), a protein kinase mediating biological effects downstream of Rho GTPases. Calcium/calmodulin-dependent protein kinase II gamma (CAMK2G/CAMK-II) is found to be one of the substrates of this phosphatase. The overexpression of this phosphatase or CAMK2G has been shown to mediate caspase-dependent apoptosis. An alternatively spliced transcript variant has been identified, but its full-length nature has not been determined. [provided by RefSeq, Jul 2008].
- Gen-ID
- 9647
- Pathways
- Positive Regulation of Endopeptidase Activity
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