CLIC4 Antikörper (AA 181-253)

Produktnummer ABIN872639

Produktdetails anti-CLIC4 Antikörper

Target: CLIC4 (Chloride Intracellular Channel 4 (CLIC4))

Bindungsspezifität: AA 181-253

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CLIC4 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CLIC4

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu CLIC4

Target: CLIC4 (Chloride Intracellular Channel 4 (CLIC4))

Andere Bezeichnung: CLIC4 (CLIC4 Produkte)

Hintergrund:

Synonyms: MC3S5, Chloride intracellular channel 4, Chloride intracellular channel 4 mitochondrial, Chloride intracellular channel 4 like, Chloride intracellular channel protein 4, Clic4, CLIC4_HUMAN, CLIC4L, DKFZP566G223, FLJ38640, H1 antibody HUH1, Intracellular chloride ion channel protein p64H1, mtCLIC, p64H1.

Background: Can insert into membranes and form poorly selective ion channels that may also transport chloride ions. Channel activity depends on the pH . Membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions. Promotes cell-surface expression of HRH3. Has alternate cellular functions like a potential role in angiogenesis or in maintaining apical-basolateral membrane polarity during mitosis and cytokinesis. Could also promote endothelial cell proliferation and regulate endothelial morphogenesis.Tissue specificity: Detected in epithelial cells from colon, esophagus and kidney (at protein level). Expression is prominent in heart, kidney, placenta and skeletal muscle.

Gen-ID: 25932