TBCD Antikörper (AA 401-500)

Produktnummer ABIN872398

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch TBCD in WB, ELISA, IF (cc), IF (p), IHC (fro) und IHC (p). Er zeigt eine Reaktivität gegenüber Maus.

Kurzübersicht für TBCD Antikörper (AA 401-500) (ABIN872398)

Target: TBCD (Tubulin Folding Cofactor D (TBCD))

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TBCD Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-TBCD Antikörper

Bindungsspezifität: AA 401-500

Kreuzreaktivität: Maus

Homologie: Human,Rat,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TBCD/Beta tubulin cofactor D

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu TBCD

Target: TBCD (Tubulin Folding Cofactor D (TBCD))

Andere Bezeichnung: Beta tubulin cofactor D

Hintergrund:

Synonyms: Beta tubulin cofactor D, Beta-tubulin cofactor D, KIAA0988, SSD 1, SSD-1, SSD1, tbcd, TBCD_HUMAN, tfcD, Tubulin folding cofactor D, Tubulin specic chaperone D, Tubulin-folding cofactor D, Tubulin-specic chaperone D.

Background: Tubulin-folding protein, involved in the first step of the tubulin folding pathway. Modulates microtubule dynamics by capturing GTP-bound beta-tubulin (TUBB). Acts as a GTPase-activating protein (GAP) for ARL2. Its ability to interact with beta tubulin is regulated via its interaction with ARL2. Induces microtubule disruption in absence of ARL2. Increases degradation of beta tubulin, when overexpressed in polarized cells. Promotes epithelial cell detachment, a process antagonized by ARL2. Induces tight adherens and tight junctions disassembly at the lateral cell membrane.

Gen-ID: 6904

Pathways: Cell-Cell Junction Organization