TBCD Antikörper

Produktnummer ABIN7120359

Produktdetails anti-TBCD Antikörper

Target: TBCD (Tubulin Folding Cofactor D (TBCD))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TBCD Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunoprecipitation (IP)

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: tubulin folding cofactor D

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:2000, IP: 1:200-1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Haltbarkeit: 12 months

Details zu TBCD

Target: TBCD (Tubulin Folding Cofactor D (TBCD))

Andere Bezeichnung: TBCD (TBCD Produkte)

Synonyme: SSD-1 antikoerper, tfcD antikoerper, 2310057L06Rik antikoerper, A030005L14Rik antikoerper, mKIAA0988 antikoerper, tubulin folding cofactor D antikoerper, tubulin-specific chaperone d antikoerper, TBCD antikoerper, Tbcd antikoerper

Hintergrund: Synonyms:KIAA0988, SSD1, TFCD Background:Tubulin-folding protein, involved in the first step of the tubulin folding pathway. Modulates microtubule dynamics by capturing GTP-bound beta-tubulin(TUBB). Acts as a GTPase-activating protein(GAP) for ARL2. Its ability to interact with beta tubulin is regulated via its interaction with ARL2. Induces microtubule disruption in absence of ARL2. Increases degradation of beta tubulin, when overexpressed in polarized cells. Promotes epithelial cell detachment, a process antagonized by ARL2. Induces tight adherens and tight junctions disassembly at the lateral cell membrane.

Molekulargewicht: 130 kDa

Gen-ID: 6904

UniProt: Q9BTW9

Pathways: Cell-Cell Junction Organization