TRERF1 Antikörper (AA 101-200)

Produktnummer ABIN872395

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch TRERF1 in ELISA, IF (cc), IF (p), IHC (p) und IHC (fro). Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für TRERF1 Antikörper (AA 101-200) (ABIN872395)

Target: TRERF1 (Transcriptional Regulating Factor 1 (TRERF1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRERF1 Antikörper ist unkonjugiert

Applikation: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-TRERF1 Antikörper

Bindungsspezifität: AA 101-200

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TReP132/RAPA

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu TRERF1

Target: TRERF1 (Transcriptional Regulating Factor 1 (TRERF1))

Andere Bezeichnung: TReP132

Hintergrund:

Synonyms: BCAR2, Breast cancer anti estrogen resistance 2, Breast cancer anti-estrogen resistance 2, RAPA, rapa 1, rapa 2, rapa1, rapa2, RP1 139D8.5, Transcriptional regulating factor 1, Transcriptional regulating protein 132, Transcriptional-regulating factor 1, Transcriptional-regulating protein 132, TREF1_HUMAN, TReP 132, TREP132, TRERF1, Zinc finger protein rapa, Zinc finger transcription factor TReP 132, Zinc finger transcription factor TReP-132.

Background: Activates transcription of CYP11A1. Interaction with CREBBP and EP300 results in a synergistic transcriptional activation of CYP11A1.Tissue specificity:Highest expression was seen in thymus, testis and adrenal cortex, expressed also in the adrenal medulla, thyroid, and stomach. Highly expressed in steroidogenic JEG-3 and MCF-7 cells, low expression was seen in non-steroidogenic HepG2 and HK293 cells.

Gen-ID: 55809

Pathways: Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Chromatin Binding