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VEGFA Antikörper (AA 81-132)

Name: VEGFA Antikörper (AA 81-132)
SKU: ABIN872390
Price: 384.62 EUR
Availability: InStock

VEGFA Reaktivität: Human, Ratte, Maus, Schaf WB, ELISA, IHC (p), IF (p), IF (cc), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated

Fasudil regulates the expression of RhoA, ROCK, p-MLC, eNOS and VEGF in placenta and umbilical vessel from PE miceWestern blot analysis for RhoA, ROCK, p-MLC, eNOS and VEGF in mice placenta and umbilical vessel, and quantification. (VEGFA Antikörper (AA 81-132))

IHC analyzes the expression of RhoA, ROCK, p-MLC, eNOS and VEGF in placenta from PE miceRepresentative images of IHC staining for RhoA, ROCK, p-MLC, eNOS and VEGF (left), and quantification (right). (VEGFA Antikörper (AA 81-132))

IHC

L1 human colon carcinoma, L2 rat heart lysates probed (ABIN872390) at 1:200 in 4 °C. (VEGFA Antikörper (AA 81-132))

SDS

3 Abbildungen

(2 Referenzen)

Produktnummer ABIN872390

Datenblatt (PDF)

Target Alle VEGFA Antikörper anzeigen

VEGFA (Vascular Endothelial Growth Factor A (VEGFA))
Bindungsspezifität
19

15

15

15

10

7

6

6

6

5

5

4

3

3

3

3

3

3

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 81-132
Reaktivität
148

100

73

22

18

17

16

10

5

5

4

3

3

2

2

2

2

1

1
Human, Ratte, Maus, Schaf
Wirt
179

57

12

2

1

1
Kaninchen
Passende Sekundärantikörper
Klonalität
192

59

1
Polyklonal
Konjugat
123

38

23

10

3

3

3

3

3

3

3

3

3

3

3

3

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1
Dieser VEGFA Antikörper ist unkonjugiert
Applikation
188

89

56

40

40

26

24

22

21

16

12

10

10

9

8

8

3

2

1

1

1

1
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität

Human, Maus, Ratte, Schaf

Homologie

Dog,Cow,Pig,Horse,Rabbit

Aufreinigung

Purified by Protein A.

Immunogen

KLH conjugated synthetic peptide derived from human VEGF-A

Isotyp

IgG

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anti-Vascular Endothelial Growth Factor A (VEGFA) antibody
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anti-Vascular Endothelial Growth Factor A (VEGFA) (AA 27-191) antibody
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anti-Vascular Endothelial Growth Factor A (VEGFA) (AA 27-130) antibody
VEGFA Reaktivität: Human WB, ELISA, PLA Wirt: Maus Monoclonal 3F7 unconjugated

anti-Vascular Endothelial Growth Factor A (VEGFA) (AA 207-371) antibody
VEGFA Reaktivität: Human WB, ELISA, FACS Wirt: Maus Monoclonal 6G5A10 unconjugated

Applikationshinweise

WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

1 μg/μL

Buffer

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel

ProClin

Vorsichtsmaßnahmen

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung

4 °C,-20 °C

Informationen zur Lagerung

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit

12 months
Li, Li, Sun, Zhou, Li, Feng, Xie: "Dual character of flavonoids in attenuating and aggravating ischemia-reperfusion-induced myocardial injury." in: Experimental and therapeutic medicine, Vol. 14, Issue 2, pp. 1307-1314, (2017) (PubMed).

Gu, Feng, Yu, Yuan, Yin, Ding, Zhao, Xu, Xu, Che: "Fasudil attenuates soluble fms-like tyrosine kinase-1 (sFlt-1)-induced hypertension in pregnant mice through RhoA/ROCK pathway." in: Oncotarget, Vol. 8, Issue 61, pp. 104104-104112, (2017) (PubMed).
Target

VEGFA (Vascular Endothelial Growth Factor A (VEGFA))

Andere Bezeichnung

VEGF-A (VEGFA Produkte)

Hintergrund

Synonyms: VPF, VEGF, MVCD1, Vascular endothelial growth factor A, VEGF-A, Vascular permeability factor, VEGFA
Background: Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. NRP1/Neuropilin-1 binds isoforms VEGF-165 and VEGF-145. Isoform VEGF165B binds to KDR but does not activate downstream signaling pathways, does not activate angiogenesis and inhibits tumor growth.

Gen-ID

7422

UniProt

P15692

Pathways

RTK Signalweg, Glycosaminoglycan Metabolic Process, Regulation of Cell Size, Tube Formation, Signaling Events mediated by VEGFR1 and VEGFR2, Platelet-derived growth Factor Receptor Signaling, VEGFR1 Specific Signals, VEGF Signaling