Inhibin alpha Antikörper
Kurzübersicht für Inhibin alpha Antikörper (ABIN865517)
Target
Alle Inhibin alpha (INHA) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Aufreinigung
- Ascitic fluid
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Immunogen
- Purified recombinant fragment of human INHA expressed in E. Coli.
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Isotyp
- IgG1
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Applikationshinweise
- WB: 1/500 - 1/2000, IF: 1/200-1/1000, ELISA: Propose dilution 1/10000.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 100g/100l
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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- Inhibin alpha (INHA) (Inhibin, alpha (INHA))
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Andere Bezeichnung
- INHA
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Hintergrund
- Inhibins are peptide hormones produced by the granulosa cells in female follicles and by Sertoli cells in the male seminiferous tubules. They are selectively expressed by cells of sex cord stromal derivation, and inhibit the secretion of follitropin by the pituitary gland. Inhibins are also involved in regulating diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins, as inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibin has 2 subunits (alpha and beta) that are coded by separate genes. The alpha subunit determines whether inhibin or activin will be produced. The alpha subunit remains constant, such that the various types of inhibin are defined by the beta subunit (a,b,c,d). Synonyms: INHA
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Molekulargewicht
- 40kDa
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Gen-ID
- 3623
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Pathways
- Peptide Hormone Metabolism, Hormone Activity, Negative Regulation of Hormone Secretion
Target
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