CDKN1C Antikörper
Kurzübersicht für CDKN1C Antikörper (ABIN865500)
Target
Alle CDKN1C Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Aufreinigung
- Ascitic fluid
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Immunogen
- Purified recombinant fragment of human CDKN1C expressed in E. Coli.
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Isotyp
- IgG1
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Applikationshinweise
- WB: 1/500 - 1/2000, ELISA: Propose dilution 1/10000.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 100g/100l
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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- CDKN1C (Cyclin-Dependent Kinase Inhibitor 1C (p57, Kip2) (CDKN1C))
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Andere Bezeichnung
- CDKN1C
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Hintergrund
- The protein encoded by this gene is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene. Tissue specificity: Expressed in the heart, brain, lung, skeletal muscle, kidney, pancreas and testis. High levels are seen in the placenta while low levels are seen in the liver. Synonyms: BWS, WBS, p57, BWCR, KIP2, CDKN1C
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Molekulargewicht
- 57kDa
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Gen-ID
- 1028
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Pathways
- Zellzyklus, Dopaminergic Neurogenesis
Target
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