PSIP1 Antikörper

Produktnummer ABIN865479

Der Maus Monoklonal anti-PSIP1 Antikörper (Klon 6E4) (ABIN865479) detektiert spezifisch PSIP1 in WB, IHC, IF und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Ratte und Affe.

Kurzübersicht für PSIP1 Antikörper (ABIN865479)

Target: PSIP1 (PC4 and SFRS1 Interacting Protein 1 (PSIP1))

Reaktivität: Human, Ratte, Affe

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PSIP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA

Klon: 6E4

Produktdetails anti-PSIP1 Antikörper

Aufreinigung: Ascitic fluid

Immunogen: Purified recombinant fragment of human CARM1 expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: WB: 1/500 - 1/2000, IHC:1/200-1/1000, IF: 1/200-1/1000, ELISA: Propose dilution 1/10000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 100g/100l

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Details zu PSIP1

Target: PSIP1 (PC4 and SFRS1 Interacting Protein 1 (PSIP1))

Andere Bezeichnung: PSIP1

Hintergrund: Transcriptional coactivator involved in neuroepithelial stem cell differentiation and neurogenesis. Involved in particular in lens epithelial cell gene regulation and stress responses. May play an important role in lens epithelial to fiber cell terminal differentiation. May play a protective role during stress-induced apoptosis. Isoform 2 is a more general and stronger transcriptional coactivator. Isoform 2 may also act as an adapter to coordinate pre-mRNA splicing. Cellular cofactor for lentiviral integration. Tissue specificity: Widely expressed. Expressed at high level in the thymus. Expressed in fetal and adult brain. Expressed in neurons, but not astrocytes. Markedly elevated in fetal as compared to adult brain. In the adult brain, expressed in the subventricular zone (SVZ), in hippocampus, and undetectable elsewhere. In the fetal brain, expressed in the germinal neuroepithelium and cortical plate regions. Synonyms: p52, p75, PAIP, DFS70, LEDGF, PSIP2, MGC74712, PSIP1

Molekulargewicht: 75kDa

Gen-ID: 11168

Pathways: Chromatin Binding, Ribonucleoprotein Complex Subunit Organization