GRK2 Antikörper
Kurzübersicht für GRK2 Antikörper (ABIN865440)
Target
Alle GRK2 (ADRBK1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Aufreinigung
- Ascitic fluid
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Immunogen
- Purified recombinant fragment of human GRK2 expressed in E. Coli.
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Isotyp
- IgG1
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Applikationshinweise
- WB: 1/500 - 1/2000, IHC: 1/200-1/1000, IF: 1/200-1/1000, ELISA: Propose dilution 1/10000.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 100g/100l
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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- GRK2 (ADRBK1) (Adrenergic, Beta, Receptor Kinase 1 (ADRBK1))
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Andere Bezeichnung
- GRK2
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Hintergrund
- The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart.Tissue specificity: Expressed in peripheral blood leukocytes Synonyms: GRK2, BARK1, FLJ16718, BETA-ARK1, ADRBK1
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Molekulargewicht
- 80kDa
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Gen-ID
- 156
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Pathways
- EGFR Signaling Pathway, Neurotrophin Signalübertragung, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling
Target
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