PRKDC Antikörper
Kurzübersicht für PRKDC Antikörper (ABIN865432)
Target
Alle PRKDC Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Aufreinigung
- Ascitic fluid
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Immunogen
- Purified recombinant fragment of human PRKDC expressed in E. Coli.
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Isotyp
- IgG1
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Applikationshinweise
- WB: 1/500 - 1/2000, IHC: 1/200-1/1000, IF: 1/200-1/1000, ELISA: Propose dilution 1/10000.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 100g/100l
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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- PRKDC (Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC))
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Andere Bezeichnung
- PRKDC
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Hintergrund
- The PRKDC gene encodes the catalytic subunit of a nuclear DNA-dependent serine/threonine protein kinase (DNA-PK). The second component is the autoimmune antigen Ku (MIM 152690), which is encoded by the G22P1 gene on chromosome 22q. On its own, the catalytic subunit of DNA-PK is inactive and relies on the G22P1 component to direct it to the DNA and trigger its kinase activity, PRKDC must be bound to DNA to express its catalytic properties. Synonyms: HYRC, p350, DNAPK, DNPK1, HYRC1, XRCC7, DNA-PKcs, PRKDC
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Molekulargewicht
- 46.9kDa
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Gen-ID
- 5591
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Pathways
- DNA Reparatur, Production of Molecular Mediator of Immune Response
Target
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