IFNAR1 Antikörper (pSer535, pSer538)
Kurzübersicht für IFNAR1 Antikörper (pSer535, pSer538) (ABIN802353)
Target
Alle IFNAR1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- pSer535, pSer538
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Kreuzreaktivität
- Human, Ratte
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Homologie
- Mouse,Dog,Cow,Sheep,Pig,Horse,Guinea Pig
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Aufreinigung
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic phosphopeptide derived from human IFNAR1 around the phosphorylation site of Ser535+Ser538
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Isotyp
- IgG
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Applikationshinweise
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ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 μg/μL
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Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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Haltbarkeit
- 12 months
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- IFNAR1 (Interferon alpha/beta Receptor 1 (IFNAR1))
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Andere Bezeichnung
- IFNAR1 +
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Hintergrund
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Synonyms: AVP, IFRC, IFNAR, IFNBR, IFN-alpha-REC, Interferon alpha/beta receptor 1, IFN-R-1, IFN-alpha/beta receptor 1, Cytokine receptor class-II member 1, Cytokine receptor family 2 member 1, CRF2-1, Type I interferon receptor 1, IFNAR1
Background: Associates with IFNAR2 to form the type I interferon receptor. Receptor for interferons alpha and beta. Binding to type I IFNs triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and IFNR alpha- and beta-subunits themselves. Can also transduce IFNB signals without the help of IFNAR2, and not activating the Jak-STAT pathway.
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Gen-ID
- 3454
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UniProt
- P17181
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Pathways
- JAK-STAT Signalweg, Hepatitis C
Target
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