Transferrin Receptor Antikörper

Produktnummer ABIN784683

Dieses Anti-Transferrin Receptor-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von Transferrin Receptor in FACS. Geeignet für Human und Affe.

Kurzübersicht für Transferrin Receptor Antikörper (ABIN784683)

Target: Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

Reaktivität: Human, Affe

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Transferrin Receptor Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS)

Klon: DF1513

Produktdetails anti-Transferrin Receptor Antikörper

Spezifität: This antibody recognizes the CD71 cell surface antigen, a 190 kDa homodimeric glycoprotein expressed by proliferating cells. CD71 acts as Receptor for Transferrin. Cross reacts with Rhesus Monkey, Mustelid.

Aufreinigung: Affinity Chromatography on Protein G

Endotoxin-Niveau: Low Endotoxin

Immunogen: KG1 cell line. Remarks: Spleen cells from immunised BALB/c mice were fused with cells of the mouse NSI myeloma cell line.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS without preservatives

Konservierungsmittel: Without preservative

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody prior to reconstitution at -20 °C. Following reconstitution the antibody can be stored at 2-8 °C for one month or at -20 °C for longer.

Details zu Transferrin Receptor

Target: Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

Andere Bezeichnung: CD71 / TFRC

Hintergrund: The transferrin receptor has been structurally characterized as a sulfide bound dimer of identical glycoprotein subunits of 95 kDa. The transferrin receptor is not present on resting blood lymphocytes. On PBL, the receptor appears after activation. The expression of transferrin receptor is coordinately regulated with cell growth. Present on T and B cell lines. The soluble (or serum) transferrin receptor (sTfR) is a circulating truncated form of the membrane receptor protein, it is an 85 kDa glycoprotein forming in serum a 320 kDa complex with diferric transferrin.The most important clinical use of the sTfR determination is in the differential diagnosis between iron deficiency anaemia and the anaemia of chronic disease.Synonyms: TfR1, Transferrin receptor protein 1, p90

Gen-ID: 7037

NCBI Accession: NP_001121620

UniProt: P02786

Pathways: Transition Metal Ion Homeostasis