IL12A Antikörper

Produktnummer ABIN784573

Dieser Ziege Polyklonal Antikörper detektiert spezifisch IL12A in IHC (p) und EIA. Es zeigt Reaktivität gegenüber Proben von Human, Hund und Schwein.

Kurzübersicht für IL12A Antikörper (ABIN784573)

Target: IL12A (Interleukin 12 alpha (IL12A))

Reaktivität: Human, Hund, Schwein

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser IL12A Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Produktdetails anti-IL12A Antikörper

Spezifität: Recognizes Interleukin-12 alpha / IL12A.

Kreuzreaktivität (Details): Species reactivity (expected):Canine (Dog), Pig.
Species reactivity (tested):Human.

Aufreinigung: Immunoaffinity Chromatography

Immunogen: Synthetic peptide - KLH conjugated of Human IL12A

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid freeze-thaw cycles.

Details zu IL12A

Target: IL12A (Interleukin 12 alpha (IL12A))

Andere Bezeichnung: Interleukin-12 alpha / IL12A

Hintergrund: Interleukin 12 (IL12) can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine activated killer cells, and stimulate the production of IFN gamma by resting PBMC. IL12 induces IFN gamma, TNF alpha production in T and NK cells, costimulation of PBL proliferation, proliferation/differentiation of TH1 T lymphocytes. It is downregulated by IL10, homodimeric p40 antagonistic to functional p70 heterodimer. IL12R beta 1 binds p40 but when dimeric with IL12R beta 2 binds p35.Synonyms: CLMF p35, Cytotoxic lymphocyte maturation factor 35 kDa subunit, IL-12 subunit p35, IL-12A, NK cell stimulatory factor chain 1, NKSF1

Gen-ID: 3592

NCBI Accession: NP_000873

Pathways: JAK-STAT Signalweg, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation