CD51 Antikörper (C-Term)

Produktnummer ABIN784042

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch CD51 in WB, IF, IHC (p) und EIA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für CD51 Antikörper (C-Term) (ABIN784042)

Target: CD51 (ITGAV) (Integrin alpha V (ITGAV))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CD51 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Produktdetails anti-CD51 Antikörper

Bindungsspezifität: C-Term

Spezifität: This antibody reacts to ITGAV / CD51.

Aufreinigung: Immunoaffinity chromatography

Immunogen: ITGAV antibody was raised against synthetic peptide

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1,0 mg/mL

Buffer: PBS (without Mg2+, Ca2+), pH 7.4, 150 mM sodium chloride, 0.02 % sodium azide, 50 % glycerol

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Details zu CD51

Target: CD51 (ITGAV) (Integrin alpha V (ITGAV))

Andere Bezeichnung: CD51 / ITGAV

Hintergrund: ITAGV encodes integrin alpha chain V. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. The I-domain containing integrin alpha V undergoes post-translational cleavage to yield disulfide-linked heavy and light chains, that combine with multiple integrin beta chains to form different integrins. Among the known associating beta chains (beta chains 1,3,5,6, and 8, 'ITGB1', 'ITGB3', 'ITGB5', 'ITGB6', and 'ITGB8'), each can interact with extracellular matrix ligands, the alpha V beta 3 integrin, perhaps the most studied of these, is referred to as the Vitronectin receptor (VNR). In addition to adhesion, many integrins are known to facilitate signal transduction.Synonyms: Integrin alpha-V, MSK8, VNRA, Vitronectin receptor subunit alpha

Gen-ID: 3685

NCBI Accession: NP_001138472

Pathways: Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Integrin Complex