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CD51 Antikörper

ITGAV Reaktivität: Human, Maus, Ratte IHC, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7074314
  • Target Alle CD51 (ITGAV) Antikörper anzeigen
    CD51 (ITGAV) (Integrin alpha V (ITGAV))
    Reaktivität
    • 98
    • 53
    • 24
    • 8
    • 7
    • 6
    • 6
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 66
    • 33
    • 9
    Kaninchen
    Klonalität
    • 56
    • 51
    Polyklonal
    Konjugat
    • 55
    • 9
    • 8
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD51 Antikörper ist unkonjugiert
    Applikation
    • 52
    • 49
    • 27
    • 25
    • 20
    • 14
    • 14
    • 12
    • 12
    • 9
    • 7
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), Immunofluorescence (IF)
    Kreuzreaktivität
    Human, Ratte
    Aufreinigung
    Affinity purification
    Immunogen
    KLH conjugated Synthetic peptide corresponding to Mouse Integrin alpha-V
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  • Applikationshinweise
    IHC/IF (H,M,R) 1:500-1:2000/1:500-1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS, pH 7.4, 0.02 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
  • Target
    CD51 (ITGAV) (Integrin alpha V (ITGAV))
    Andere Bezeichnung
    Integrin alpha V (ITGAV Produkte)
    Synonyme
    1110004F14Rik antikoerper, 2610028E01Rik antikoerper, CD51 antikoerper, D430040G12Rik antikoerper, MSK8 antikoerper, VNRA antikoerper, VTNR antikoerper, Cd51 antikoerper, integrin subunit alpha V antikoerper, integrin alpha V antikoerper, ITGAV antikoerper, Itgav antikoerper
    Hintergrund
    The alpha-V (ITGAV) integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and vWF. They recognize the sequence R-G-D in a wide array of ligands. ITGAV:ITGB3 binds to fractalkine (CX3CL1) and may act as its coreceptor in CX3CR1-dependent fractalkine signaling . ITGAV:ITGB3 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling. ITGAV:ITGB3 binds to FGF1 and this binding is essential for FGF1 signaling . ITGAV:ITGB3 binds to IGF1 and this binding is essential for IGF1 signaling. ITGAV:ITGB3 binds to PLA2G2A via a site (site 2) which is distinct from the classical ligand-binding site (site 1) and this induces integrin conformational changes and enhanced ligand binding to site 1.
    Gen-ID
    16410
    NCBI Accession
    NP_032428
    UniProt
    P43406
    Pathways
    Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Integrin Complex
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