Endonuclease G Antikörper
Kurzübersicht für Endonuclease G Antikörper (ABIN783844)
Target
Alle Endonuclease G (ENDOG) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Spezifität
- This antibody recognizes ~35 kDa EndoG.
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Kreuzreaktivität (Details)
- Species reactivity (tested):Human, mouse, rat
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Aufreinigung
- Affinity chromatography
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Immunogen
- Synthetic peptide surrounding amino acid 280 of rat EndoG
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 0.5 mg/mL
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Buffer
- Phosphate buffered saline (PBS), pH 7.2, containing 30 % glycerol, 0.5 % BSA, 0.01 % thimerosal
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Konservierungsmittel
- Thimerosal (Merthiolate)
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Vorsichtsmaßnahmen
- This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Upon receipt, store at -20 °C. For long term storage, aliquot and store at -70 °C.
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- Endonuclease G (ENDOG)
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Andere Bezeichnung
- Endonuclease G
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Hintergrund
- Endonuclease G (EndoG) is a mitochondrion-specific nuclease that specifically activated by apoptotic stimuli and translocates to the nucleus during apoptosis. In nucleus, EndoG induces nucleosomal fragmentation of DNA independent of caspase and DFF/CAD.Synonyms: ENDOG
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Gen-ID
- 2021
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NCBI Accession
- NP_004426
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UniProt
- Q14249
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Pathways
- Apoptose
Target
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