CDC23 Antikörper (Center)
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- Target Alle CDC23 Antikörper anzeigen
- CDC23 (Cell Division Cycle 23 (CDC23))
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Bindungsspezifität
- Center
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CDC23 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Kreuzreaktivität (Details)
- Species reactivity (tested):Human, mouse, rat
- Aufreinigung
- Affinity chromatography purified via peptide column
- Immunogen
- 17 amino acid peptide near the center of human APC8
- Top Product
- Discover our top product CDC23 Primärantikörper
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anti-Cell Division Cycle 23 (CDC23) (AA 366-597) antibody
CDC23 Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Cell Division Cycle 23 (CDC23) (AA 50-150) antibodyCDC23 Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Cell Division Cycle 23 (CDC23) antibodyCDC23 Reaktivität: Human, Maus, Ratte IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Cell Division Cycle 23 (CDC23) (AA 491-591) antibodyCDC23 Reaktivität: Human WB, ELISA, IF Wirt: Maus Monoclonal 1F3 unconjugated
anti-Cell Division Cycle 23 (CDC23) (Internal Region) antibodyCDC23 Reaktivität: Human, Maus, Affe WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-Cell Division Cycle 23 (CDC23) (AA 140-168), (N-Term) antibodyCDC23 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB19769 unconjugated
anti-Cell Division Cycle 23 (CDC23) (Internal Region) antibodyCDC23 Reaktivität: Human, Maus WB, ELISA, ICC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Cell Division Cycle 23 (CDC23) antibodyCDC23 Reaktivität: Human WB, IF Wirt: Kaninchen Monoclonal unconjugated
anti-Cell Division Cycle 23 (CDC23) (AA 62-142) antibodyCDC23 Reaktivität: Human ELISA, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Cell Division Cycle 23 (CDC23) (AA 101-150) antibodyCDC23 Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen, Affe, Xenopus laevis, Huhn, Zebrafisch (Danio rerio), Fledermaus, Schwein WB Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1.0 mg/mL
- Buffer
- PBS containing 0.02 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store the antibody (in aliquots) at -20 °C.
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- Target
- CDC23 (Cell Division Cycle 23 (CDC23))
- Andere Bezeichnung
- CDC23 / APC8 (CDC23 Produkte)
- Hintergrund
- Cell cycle regulated protein ubiquitination and degradation within subcellular domains is thought to be essential for the normal progression of mitosis. APC8 is a highly conserved component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. APC/C is responsible for degrading anaphase inhibitors, mitotic cyclins, and spindle-associated proteins ensuring that events of mitosis take place in proper sequence. The individual APC/C components mRNA and protein levels are expressed at approximately the same levels in most tissues and cell lines, suggesting that they perform their functions as part of a complex. In Drosophila, silencing of APC8 results in developmental delay and pupal lethality with elevated levels of apoptosis, high mitotic index, and delayed or blocked mitosis.Synonyms: ANAPC8, Anaphase-promoting complex subunit 8, Cell division cycle protein 23 homolog, Cyclosome subunit 8
- Gen-ID
- 8697
- NCBI Accession
- NP_004652
- UniProt
- Q9UJX2
- Pathways
- Protein targeting to Nucleus
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