KPNA4 Antikörper (N-Term)

Produktnummer ABIN783731

Produktdetails anti-KPNA4 Antikörper

Target: KPNA4 (Karyopherin (Importin) alpha 4 (KPNA4))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KPNA4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Spezifität: This antibody detects KPNA4 / Importin alpha-4 at N-term.

Kreuzreaktivität (Details): Species reactivity (tested):Human, mouse, rat

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 15 amino acid peptide near the amino terminus of human KPNA4

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.

Details zu KPNA4

Target: KPNA4 (Karyopherin (Importin) alpha 4 (KPNA4))

Andere Bezeichnung: KPNA4 / Importin alpha-4 (KPNA4 Produkte)

Synonyme: IPOA3 antikoerper, QIP1 antikoerper, SRP3 antikoerper, 6 antikoerper, ATIMPALPHA3 antikoerper, IMPA-3 antikoerper, IMPORTIN ALPHA 3 antikoerper, IMPORTIN ALPHA ISOFORM 3 antikoerper, MODIFIER OF SNC1 antikoerper, T10M13.16 antikoerper, T10M13_16 antikoerper, LOC100224013 antikoerper, 1110058D08Rik antikoerper, importin antikoerper, ipoa3 antikoerper, qip1 antikoerper, srp3 antikoerper, impa3 antikoerper, wu:fa56d07 antikoerper, wu:fa66g10 antikoerper, wu:fe14c04 antikoerper, wu:fi04h11 antikoerper, wu:fi19b05 antikoerper, karyopherin subunit alpha 4 antikoerper, ARM repeat superfamily protein antikoerper, importin alpha 3 antikoerper, karyopherin (importin) alpha 4 antikoerper, karyopherin alpha 4 (importin alpha 3) S homeolog antikoerper, karyopherin alpha 4 (importin alpha 3) antikoerper, KPNA4 antikoerper, MOS6 antikoerper, LOC100533341 antikoerper, Kpna4 antikoerper, kpna4.S antikoerper, kpna4 antikoerper

Hintergrund: Karyopherin, a cytosolic and heterodimeric protein complex consisting of alpha and beta subunits, is responsible for targeting proteins with nuclear localization signals to the nuclear pore complex by an energy requiring, Ran-dependent mechanism. The alpha subunit and imported substrate enter the nucleus and accumulate in the nucleoplasm, while the beta subunit accumulates at the NPC. Molecules containing the classical nuclear localization signal (NLS) are transported into the nucleus by alpha/beta heterodimers. KPNA3 has been shown to be important in the TNF-alpha-induced nuclear import of NF-kappaB. It is also involved in the stress-mediated nuclear stabilization of p53 and the nuclear import and replication of HIV-1 in both dividing and non-dividing cells.Synonyms: Importin alpha Q1, Karyopherin subunit alpha-4, QIP1

Gen-ID: 3840

NCBI Accession: NP_002259

UniProt: O00629

Pathways: Protein targeting to Nucleus