NLRP14 Antikörper (N-Term)

Produktnummer ABIN783723

Der Kaninchen Polyklonal anti-NLRP14 Antikörper (ABIN783723) detektiert spezifisch NLRP14 in WB und EIA. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für NLRP14 Antikörper (N-Term) (ABIN783723)

Target: NLRP14 (NLR Family, Pyrin Domain Containing 14 (NLRP14))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NLRP14 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-NLRP14 Antikörper

Bindungsspezifität: N-Term

Spezifität: This antibody detects NALP14 at N-term.

Kreuzreaktivität (Details): Species reactivity (tested):Human, mouse, rat

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 16 amino acid peptide near the amino terminus of human NALP14

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.

Details zu NLRP14

Target: NLRP14 (NLR Family, Pyrin Domain Containing 14 (NLRP14))

Andere Bezeichnung: NLRP14

Hintergrund: NALP proteins are cytoplasmic proteins that form a subfamily within the larger CATERPILLER family and are thought to play a crucial role in cell proliferation and reproduction. Like all other NALP family members, NALP14 has a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain. While little is known about the function of NALP14, it has been suggested that it may play a role in spermatogenesis and that mutations in the NALP14 gene might cause spermatogenic failure.Synonyms: NACHT LRR and PYD domains-containing protein 14, NALP14, NOD5, Nucleotide-binding oligomerization domain protein 5

Gen-ID: 338323

NCBI Accession: NP_789792

UniProt: Q86W24

Pathways: Inflammasome