Secernin 1 Antikörper (C-Term)

Produktnummer ABIN783653

Der Kaninchen Polyklonal Anti-Secernin 1-Antikörper wurde für WB, IF und EIA validiert. Er ist geeignet, Secernin 1 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für Secernin 1 Antikörper (C-Term) (ABIN783653)

Target: Secernin 1 (SCRN1)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Secernin 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Produktdetails anti-Secernin 1 Antikörper

Bindungsspezifität: C-Term

Kreuzreaktivität (Details): Species reactivity (tested):Human, mouse, rat

Immunogen: 20 amino acid peptide near the carboxy terminus of human SCRN1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store the antibody (in aliquots) at -20 °C.

Details zu Secernin 1

Target: Secernin 1 (SCRN1)

Andere Bezeichnung: Secernin-1 (SCRN1)

Hintergrund: SCRN1 was first identified as a cytosolic protein that is involved in the regulation of exocytosis from peritoneal mast cells. More recent studies have shown that SCRN1 expression is upregulated in gastric cancer cell lines and may possess epitopes that could function as tumor-associated antigens, potentially providing targets for cancer vaccines in the treatment of gastric cancers. Another report indicates that decreased expression of SCRN1 via RNAi expression resulted in significantly lower rates of cell growth in colorectal cancer cell lines, and increased SCRN1 expression in patients with colorectal cancer correlated with poor prognosis, suggesting that SCRN1 may also be involved in the regulation of cell growth and might be useful as a prognostic tool.Synonyms: KIAA0193

Gen-ID: 9805

NCBI Accession: NP_001138985

UniProt: Q12765