ZEB1 Antikörper (Center)
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- Target Alle ZEB1 Antikörper anzeigen
- ZEB1 (Zinc Finger E-Box Binding Homeobox 1 (ZEB1))
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Bindungsspezifität
- Center
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser ZEB1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
- Kreuzreaktivität (Details)
- Species reactivity (tested):Human
- Aufreinigung
- Affinity chromatography purified via peptide column
- Immunogen
- 15 amino acid peptide near the center of human ZEB1
- Top Product
- Discover our top product ZEB1 Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1.0 mg/mL
- Buffer
- PBS containing 0.02 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store the antibody (in aliquots) at -20 °C.
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- Target
- ZEB1 (Zinc Finger E-Box Binding Homeobox 1 (ZEB1))
- Andere Bezeichnung
- ZEB1 (ZEB1 Produkte)
- Hintergrund
- ZEB1, initially identified as the delta-crystallin enhancer binding protein delta EF1, is a DNA-binding protein that binds to a modified E-box sequence and has been implicated in postgastrulation embryogenesis. ZEB1 binds to the promoter of several hemapoietic genes, including interleukin-2, CD4, GATA-3, and alpha(4)-integrin, and mice in which ZEB1 has been targeted show thymic atrophy, and severe defects in lymphocyte differentiation. Recent evidence suggests that ZEB1 also regulates the accumulation of adipose tissue and may play a role in obesity. Mutations in this gene have been associated with late-onset Fuchs endothelial corneal dystrophy.Synonyms: AREB6, NIL-2-A, NIL-2-A zinc finger protein, Negative regulator of IL2, TCF-8, TCF8, Transcription factor 8, Zinc finger E-box-binding homeobox 1
- Gen-ID
- 6935
- NCBI Accession
- NP_001121600
- UniProt
- P37275
- Pathways
- Regulation of Muscle Cell Differentiation
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