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IDH2 Antikörper (C-Term)
IDH2
Reaktivität: Human, Maus, Ratte
WB, EIA
Wirt: Kaninchen
Polyclonal
unconjugated
Produktdetails anti-IDH2 Antikörper
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Target
Alle IDH2 Antikörper anzeigen
IDH2
(Isocitrate Dehydrogenase 2 (NADP+), Mitochondrial (IDH2))
Bindungsspezifität
Alle Epitope für IDH2 Antikörper
C-Term
Reaktivität
Alle Reaktivitäten für IDH2 Antikörper
Human, Maus, Ratte
Wirt
Alle Wirte für IDH2 Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für IDH2 Antikörper
Polyklonal
Konjugat
Alle Konjugate für IDH2 Antikörper
Dieser IDH2 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für IDH2 Antikörper
Western Blotting (WB), Enzyme Immunoassay (EIA)
Kreuzreaktivität (Details)
Species reactivity (tested):Human, mouse, rat
Aufreinigung
Affinity chromatography purified via peptide column
Immunogen
13 amino acid peptide near the carboxy terminus of human IDH1
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Discover our top product IDH2 Primärantikörper
Alternativen
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anti-Isocitrate Dehydrogenase 2 (NADP+), Mitochondrial (IDH2) (Middle Region) antibody
IDH2
Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Kaninchen, Pferd, Zebrafisch (Danio rerio), Meerschweinchen, Saccharomyces cerevisiae
WB
Wirt: Kaninchen
Polyclonal
unconjugated
Anwendungsinformationen
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Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Konzentration
1.0 mg/mL
Buffer
PBS containing 0.02 % sodium azide
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
-20 °C
Informationen zur Lagerung
Store the antibody (in aliquots) at -20 °C.
Details zu IDH2
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Target
IDH2
(Isocitrate Dehydrogenase 2 (NADP+), Mitochondrial (IDH2))
Andere Bezeichnung
Isocitrate Dehydrogenase / IDH2 (IDH2 Produkte )
Synonyme
F6P23.14 antikoerper, F6P23_14 antikoerper, IDH-II antikoerper, NAD+ DEPENDENT ISOCITRATE DEHYDROGENASE SUBUNIT 2 antikoerper, isocitrate dehydrogenase II antikoerper, isocitrate dehydrogenase subunit 2 antikoerper, D2HGA2 antikoerper, ICD-M antikoerper, IDH antikoerper, IDHM antikoerper, IDP antikoerper, IDPM antikoerper, mNADP-IDH antikoerper, E430004F23 antikoerper, IDPm antikoerper, Idh-2 antikoerper, wu:fb33c06 antikoerper, wu:fk31e05 antikoerper, wu:fq43b01 antikoerper, zgc:55485 antikoerper, idh2 antikoerper, IDH2 antikoerper, isocitrate dehydrogenase subunit 2 antikoerper, isocitrate dehydrogenase (NADP(+)) 2, mitochondrial antikoerper, isocitrate dehydrogenase 2 (NADP+), mitochondrial antikoerper, isocitrate dehydrogenase 2 (NADP+), mitochondrial S homeolog antikoerper, isocitrate dehydrogenase [NADP], mitochondrial antikoerper, IDH2 antikoerper, Idh2 antikoerper, idh2.S antikoerper, idh2 antikoerper, LOC100441867 antikoerper
Hintergrund
Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Two NADP(+)-dependent isocitrate dehydrogenases have been found as homodimer: IDH1 is predominantly cytosolic and peroxisomal and IDH2 is mitochondrial. The presence of IDH1 in peroxisomes suggests it may play a role in the regeneration of NADPH for intraperoxisomal reductions, such as the conversion of 2, 4-dienoyl-CoAs to 3-enoyl-CoAs, as well as in peroxisomal reactions that consume 2-oxoglutarate, namely the alpha-hydroxylation of phytanic acid. The cytoplasmic IDH1 serves a significant role in cytoplasmic NADPH production. Defects in IDH1 are involved in the development of glioma.Synonyms: ICD-M, ICDH, IDP, NADP(+)-specific ICDH, mitochondrial Isocitrate dehydrogenase [NADP], mitochondrial Oxalosuccinate decarboxylase
Gen-ID
3418
NCBI Accession
NP_002159
UniProt
P48735
Pathways
Warburg Effekt
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