SIRT4 Antikörper (N-Term)
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- Target Alle SIRT4 Antikörper anzeigen
- SIRT4 (Sirtuin 4 (SIRT4))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human, Maus, Ratte
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Wirt
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Huhn
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Klonalität
- Polyklonal
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Konjugat
- Dieser SIRT4 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Kreuzreaktivität (Details)
- Species reactivity (tested):Human, mouse, rat
- Aufreinigung
- Affinity chromatography purified via peptide column
- Immunogen
- 17 amino acid peptide near the amino terminus of human SIRT4
- Top Product
- Discover our top product SIRT4 Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1.0 mg/mL
- Buffer
- PBS containing 0.02 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store the antibody (in aliquots) at -20 °C.
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- Target
- SIRT4 (Sirtuin 4 (SIRT4))
- Andere Bezeichnung
- SIRT4 (SIRT4 Produkte)
- Synonyme
- SIRT4 antikoerper, im:7139453 antikoerper, SIR2L4 antikoerper, 4930596O17Rik antikoerper, sirtuin 4 antikoerper, SIRT4 antikoerper, sirt4 antikoerper, Sirt4 antikoerper
- Hintergrund
- The Silent Information Regulator (SIR2) family of genes are highly conserved from prokaryotes to eukaryotes and have important functions in the regulation of metabolism, growth and differentiation, inflammation, cellular survival, as well as in senescence and lifespan extension. Sirtuins, including SIRT1-7, are human homologs of yeast Sir2p. Sirtuins are NAD+-dependent histone/protein deacetylases (HDAC) which regulate cellular metabolism, e.g. energy metabolism, and thereby are associated with aging and several age-related diseases. SIRT4 localizes to mitochondria, inhibits glutamate dehydrogenase, and is thought to be involved in the regulation of insulin secretion.Synonyms: NAD-Dependent ADP-Ribosyltransferase Sirtuin-4, SIR2-like 4, SIR2L4, SIRT-4, sirtuin (silent mating type information regulation 2 homolog) 4 (S. cerevisiae), sirtuin 4, sirtuin type 4, sirtuin-4
- Gen-ID
- 23409
- NCBI Accession
- NP_036372
- UniProt
- Q9Y6E7
- Pathways
- Negative Regulation of Hormone Secretion
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