SIRT4 Antikörper (C-Term)

Produktnummer ABIN185191

Produktdetails anti-SIRT4 Antikörper

Target: SIRT4 (Sirtuin 4 (SIRT4))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser SIRT4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Verwendungszweck: SIRT4

Sequenz: SRCGELLPLI DPC

Kreuzreaktivität: Rind (Kuh), Hund, Human, Maus, Schwein, Ratte

Aufreinigung: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Güteklasse: Verified

Immunogen: Peptide with sequence SRCGELLPLIDPC, from the C Terminus of the protein sequence according to NP_036372.1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

Immunohistochemistry: In paraffin embedded Skeletal Muscle shows spotty staining of striated fibres in longitudinal section. Recommended concentration: 2-3 μg/mL.

Western Blot: Approx. 38 kDa band observed in Human Kidney lysates (calculated MW of 35.2 kDa according to NP_036372.1). Recommended concentration: 1-3 μg/mL. Primary incubation was 1 hour.

Peptide ELISA: antibody detection limit dilution 1:32000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Minimize freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.

Referenzen für anti-SIRT4 Antikörper (ABIN185191)

do Amaral, Ueno, Oliveira, Borsonello, Vanzela, Ribeiro, Alves, Barbosa, Carneiro, Boschero: "Reduced expression of SIRT1 is associated with diminished glucose-induced insulin secretion in islets from calorie-restricted rats." in: The Journal of nutritional biochemistry, Vol. 22, Issue 6, pp. 554-9, (2011) (PubMed).

Details zu SIRT4

Target: SIRT4 (Sirtuin 4 (SIRT4))

Andere Bezeichnung: SIRT4 (SIRT4 Produkte)

Synonyme: SIRT4 antikoerper, im:7139453 antikoerper, SIR2L4 antikoerper, 4930596O17Rik antikoerper, sirtuin 4 antikoerper, SIRT4 antikoerper, sirt4 antikoerper, Sirt4 antikoerper

Hintergrund: SIRT4, SIR2L4, sirtuin (silent mating type information regulation 2 homolog) 4 (S. cerevisiae), sirtuin silent mating type information regulation 2 homolog 4 (S. cerevisiae), MGC130046, MGC130047, MGC57437, SIR2L4, sirtuin 4, sir2-like 4, sirtuin 4, sirtu

Gen-ID: 23409, 75387

NCBI Accession: NP_036372

Pathways: Negative Regulation of Hormone Secretion