SGK1 Antikörper (C-Term)

Produktnummer ABIN783476

Der Kaninchen Polyklonal Anti-SGK1-Antikörper wurde für WB und EIA validiert. Er ist geeignet, SGK1 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für SGK1 Antikörper (C-Term) (ABIN783476)

Target: SGK1 (serum/glucocorticoid Regulated Kinase 1 (SGK1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SGK1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-SGK1 Antikörper

Bindungsspezifität: C-Term

Spezifität: This antibody detects SGK1 / SGK at C-term. SGK1 antibody is predicted to not cross-react with other SGK protein family members.

Kreuzreaktivität (Details): Species reactivity (tested):Human, mouse, rat

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 18 amino acid peptide near the carboxy terminus of human SGK1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.

Details zu SGK1

Target: SGK1 (serum/glucocorticoid Regulated Kinase 1 (SGK1))

Andere Bezeichnung: SGK1 / SGK

Hintergrund: Serum and glucocorticoid-regulated protein kinase 1 (SGK1) is a member of the AGC family of serine/threonine kinases that plays an important role in cellular stress response and cell survival. SGK1 is transcriptionally activated by numerous stimuli, including serum, glucocorticoids, osmotic stress, and hormones. SGK1 functions as a regulator of cell survival and ion channels and transporters such as ENaC or KCNA3/Kv1.3. It phosphorylates and negatively regulates pro-apoptotic FOXO3A. SGK1 is thought to play an essential function in nephropathy and cardiovascular development. At least five isoforms of SGK1 are known to exist.Synonyms: Serine/threonine-protein kinase Sgk1, Serum/glucocorticoid-regulated kinase 1

Gen-ID: 6446

NCBI Accession: NP_001137148

UniProt: O00141

Pathways: MAPK Signalweg, Notch Signalweg, Steroid Hormone Mediated Signaling Pathway