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PRR5L Antikörper (Center)

PRR5L Reaktivität: Human WB, EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN783444
  • Target Alle PRR5L Antikörper anzeigen
    PRR5L (Proline Rich 5 Like (PRR5L))
    Bindungsspezifität
    • 1
    • 1
    Center
    Reaktivität
    • 3
    • 1
    Human
    Wirt
    • 3
    Kaninchen
    Klonalität
    • 3
    Polyklonal
    Konjugat
    • 3
    Dieser PRR5L Antikörper ist unkonjugiert
    Applikation
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Spezifität
    This antibody detects PRR5L at Center. At least three isoforms of PRR5L are known to exist, this antibody will recognize only isoforms a and b. PRR5L antibody will not cross-react with PPR5.
    Kreuzreaktivität (Details)
    Species reactivity (tested):Human, mouse
    Aufreinigung
    Affinity chromatography purified via peptide column
    Immunogen
    17 amino acid peptide near the center of human PRR5L
    Top Product
    Discover our top product PRR5L Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS containing 0.02 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
  • Target
    PRR5L (Proline Rich 5 Like (PRR5L))
    Andere Bezeichnung
    PRR5L (PRR5L Produkte)
    Synonyme
    PROTOR2 antikoerper, 2600010E01Rik antikoerper, 4833411O04Rik antikoerper, Protor-2 antikoerper, Protor2 antikoerper, RGD1309969 antikoerper, PRR5L antikoerper, FLJ14213 antikoerper, proline rich 5 like antikoerper, PRR5L antikoerper, Prr5l antikoerper, prr5l antikoerper
    Hintergrund
    Proline-rich protein 5-like (PRR5L), also known as Protor-2, is structurally similar to PRR5 and also binds to the mTOR complex 2 (mTORC2). PRR5L is not required for mTORC2 integrity or kinase activity, but dissociates from mTORC2 upon knockdown of tuberous sclerosis complex 1 (TSC1) and TSC2. Knockdown of PRR5L reduced apoptosis in mTORC2 deficient cells as well as cells where mTOR was active, suggesting that mTORC2-dissociated PRR5L may promote apoptosis, and thus play a role in the balance between cell growth and cell death.Synonyms: FLJ14213, PROTOR2, Proline-rich protein 5-like, Protein observed with Rictor-2
    Gen-ID
    79899
    NCBI Accession
    NP_001153639
    UniProt
    Q6MZQ0
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