CTNNBL1 Antikörper (C-Term)

Produktnummer ABIN783411

Der Kaninchen Polyklonal anti-CTNNBL1 Antikörper (ABIN783411) detektiert spezifisch CTNNBL1 in WB und EIA. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für CTNNBL1 Antikörper (C-Term) (ABIN783411)

Target: CTNNBL1 (Catenin, beta Like 1 (CTNNBL1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CTNNBL1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-CTNNBL1 Antikörper

Bindungsspezifität: C-Term

Spezifität: This antibody detects CTNNBL1 at C-term. CTNNBL1 antibody is predicted to not cross-react with other catenin family members. At least four isoforms of CTNNBL1 are known to exist, this antibody will detect all but isoform b.

Kreuzreaktivität (Details): Species reactivity (tested):Human, mouse, rat

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 20 amino acid peptide near the carboxy terminus of human CTTNBL1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.

Details zu CTNNBL1

Target: CTNNBL1 (Catenin, beta Like 1 (CTNNBL1))

Andere Bezeichnung: CTNNBL1

Hintergrund: The Beta-catenin-like protein 1 (CTNNBL1) contains an acidic domain, a putative bipartite nuclear localization signal, a nuclear export signal, a leucine-isoleucine zipper, and phosphorylation motifs, as well as Armadillo/beta-catenin-like repeats. Transient expression of CTNNBL1 resulted in translocation to the nucleus and apoptosis, suggesting it may be involved in the apoptotic pathway. CTNNBL1 interacts with the Prp19 complex of the spliceosome and the Ig class switching enzyme activation-induced deaminase (AID) and had been suggested to play a role in antibody-diversification and class switching, but recent studies have shown CTNNBL1 to be dispensable for Ig class switch recombination. Other studies have identified CTTNBL1 as a novel gene for obesity.Synonyms: Beta-catenin-like protein 1, C20orf33, NYD-SP19, Nuclear-associated protein, Testis development protein NYD-SP19

Gen-ID: 56259

NCBI Accession: NP_110517

UniProt: Q8WYA6

Pathways: Production of Molecular Mediator of Immune Response