Der Kaninchen Polyklonal Anti-VPS39-Antikörper wurde für WB und EIA validiert. Er ist geeignet, VPS39 in Proben von Human, Maus und Ratte zu detektieren.
This antibody detects VPS39 / VAM6 at C-term. At least four isoforms of VPS39 are known to exist, this antibody will detect all four. VPS39 antibody is predicted not to cross-react with TRAP1.
Kreuzreaktivität (Details)
Species reactivity (tested):Human, mouse, rat
Aufreinigung
Affinity chromatography purified via peptide column
Immunogen
18 amino acid peptide near the carboxy terminus of human VPS39
VPS39
Reaktivität: Human
ELISA
Wirt: Kaninchen
Polyclonal
FITC
Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Buffer
PBS containing 0.02 % sodium azide
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
Target
VPS39
(Vacuolar Protein Sorting 39 Homolog (VPS39))
Andere Bezeichnung
VPS39
Hintergrund
VPS39 is the mammalian homolog of the yeast vacuolar protein VAM6, that in mammals, promotes lysosome clustering and fusion in vivo. VPS39 is also thought to modulate the TGF-b response by coupling the TGF-b receptor complex to the Smad pathway. Similar to the related protein TRAP1, the VPS39 protein is essential for early embryonic development, with mice lacking VPS39 dying at or before E6.5.Synonyms: KIAA0770, VAM6, Vam6/Vps39-like protein