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LRRTM3 Antikörper (C-Term)

LRRTM3 Reaktivität: Maus, Human, Ratte WB, EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN783383
  • Target Alle LRRTM3 Antikörper anzeigen
    LRRTM3 (Leucine Rich Repeat Transmembrane Neuronal 3 (LRRTM3))
    Bindungsspezifität
    • 16
    • 2
    • 2
    • 1
    C-Term
    Reaktivität
    • 24
    • 8
    • 7
    • 6
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Maus, Human, Ratte
    Wirt
    • 23
    • 1
    • 1
    Kaninchen
    Klonalität
    • 24
    • 1
    Polyklonal
    Konjugat
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser LRRTM3 Antikörper ist unkonjugiert
    Applikation
    • 24
    • 18
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Spezifität
    This antibnody detects LRRTM3 at C-term. At least two isoforms of LRRTM3 are known to exist, this antibody will only detect the larger isoform.
    Kreuzreaktivität (Details)
    Species reactivity (tested):Human, mouse, rat
    Aufreinigung
    Affinity chromatography purified via peptide column
    Immunogen
    18 amino acid peptide near the carboxy terminus of human LRRTM3
    Top Product
    Discover our top product LRRTM3 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS containing 0.02 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
  • Target
    LRRTM3 (Leucine Rich Repeat Transmembrane Neuronal 3 (LRRTM3))
    Andere Bezeichnung
    LRRTM3 (LRRTM3 Produkte)
    Synonyme
    9630044H04Rik antikoerper, leucine rich repeat transmembrane neuronal 3 antikoerper, LRRTM3 antikoerper, lrrtm3 antikoerper, Lrrtm3 antikoerper
    Hintergrund
    The Leucine-rich repeat transmembrane neuronal proteins (LRRTMs) are differentially expressed in the nervous system and were recently found to instruct presynaptic and mediate postsynaptic glutamatergic differentiation, with LRRTM1 and LRRTM2 most potent at inducing presynaptic differentiation. Recent evidence suggests that LRRTM3 promotes the processing of amyloid-precursor protein (APP) by the β-secretase BACE, leading to the proteolytic production of the Aβ42 peptide that is the main component of amyloid plaques. Furthermore, LRRTM3 maps to a region of chromosome 10 linked to both late-onset Alzheimer's disease (AD) and elevated plasma Aβ42 levels, suggesting that LRRTM3 is a functional and positional candidate gene for AD.Synonyms: Leucine-rich repeat transmembrane neuronal protein 3
    Gen-ID
    26045
    NCBI Accession
    NP_056379
    UniProt
    Q86VH5
    Pathways
    Synaptic Membrane
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