CXXC5 Antikörper (N-Term)

Produktnummer ABIN783347

Der Kaninchen Polyklonal anti-CXXC5 Antikörper wird verwendet zum Nachweis von CXXC5 in Proben von Human, Maus und Ratte. Er wurde validiert für WB und EIA.

Kurzübersicht für CXXC5 Antikörper (N-Term) (ABIN783347)

Target: CXXC5 (CXXC Finger Protein 5 (CXXC5))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CXXC5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-CXXC5 Antikörper

Bindungsspezifität: N-Term

Spezifität: This antibody detects CXXC5 at N-term. At least two isoforms of CXXC5 are known to exist. CXXC5 antibody is predicted to not cross-react with other CXXC protein family members.

Kreuzreaktivität (Details): Species reactivity (tested):Human, mouse, rat

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 15 amino acid peptide near the amino terminus of human CXXC5

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.

Details zu CXXC5

Target: CXXC5 (CXXC Finger Protein 5 (CXXC5))

Andere Bezeichnung: CXXC5

Hintergrund: CXXC5 is zinc finger protein closely related to the DVL1-binding protein CXXC4 (also known as Idax), and like CXXC4 is thought to modulate the Wnt signaling pathway during development. CXXC5 is upregulated in neural stem cells upon BMP4 stimulation, leading to decreased levels of the Wnt-signaling target AXIN2 and facilitated the response of the stem cells to Wnt3a. Recent reports suggest CXXC5 transcription is activated by the Wilms tumor 1 (WT1) transcription factor, and together are involved in the WNT/beta-catenin pathway and play a role in embryonic kidney development.Synonyms: CXXC-type zinc finger protein 5, PM08, Putative MAPK-activating protein PM08, Putative NF-kappa-B-activating protein 102

Gen-ID: 51523

NCBI Accession: NP_057547

UniProt: Q7LFL8