CXXC5 Antikörper (N-Term)

Produktnummer ABIN6991464

Der Kaninchen Polyklonal anti-CXXC5 Antikörper (ABIN6991464) detektiert spezifisch CXXC5 in WB, ELISA, IHC (p) und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für CXXC5 Antikörper (N-Term) (ABIN6991464)

Target: CXXC5 (CXXC Finger Protein 5 (CXXC5))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CXXC5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Produktdetails anti-CXXC5 Antikörper

Bindungsspezifität: AA 30-80, N-Term

Spezifität: At least two isoforms of CXXC5 are known to exist. CXXC5 antibody is predicted to not cross-react with other CXXC protein family members.

Aufreinigung: CXXC5 Antibody is affinity chromatography purified via peptide column.

Immunogen: CXXC5 antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human CXXC5. The immunogen is located within amino acids 30 - 80 of CXXC5.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: CXXC5 antibody can be used for detection of CXXC5 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: CXXC5 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: CXXC5 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu CXXC5

Target: CXXC5 (CXXC Finger Protein 5 (CXXC5))

Andere Bezeichnung: CXXC5

Hintergrund: CXXC5 Antibody: CXXC5 is zinc finger protein closely related to the DVL1-binding protein CXXC4 (also known as Idax), and like CXXC4 is thought to modulate the Wnt signaling pathway during development. CXXC5 is upregulated in neural stem cells upon BMP4 stimulation, leading to decreased levels of the Wnt-signaling target AXIN2 and facilitated the response of the stem cells to Wnt3a. Recent reports suggest CXXC5 transcription is activated by the Wilms tumor 1 (WT1) transcription factor, and together are involved in the WNT/beta-catenin pathway and play a role in embryonic kidney development.

Molekulargewicht: Predicted: 25, 35 kDa

Observed: 25, 35 kDa

Gen-ID: 51523

NCBI Accession: NP_057547

UniProt: Q7LFL8