VAMP1 Antikörper

Produktnummer ABIN782443

Dieser Maus Monoklonal Antikörper detektiert spezifisch VAMP1 in WB und IHC (fro). Es zeigt Reaktivität gegenüber Proben von Human, Ratte, Maus, Rind (Kuh), Kaninchen, Schwein und Hamster.

Kurzübersicht für VAMP1 Antikörper (ABIN782443)

Target: VAMP1 (Vesicle-Associated Membrane Protein 1 (Synaptobrevin 1) (VAMP1))

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Kaninchen, Schwein, Hamster

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser VAMP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro))

Klon: SP10

Produktdetails anti-VAMP1 Antikörper

Spezifität: The antibody is specific for the ~16 kDa synaptobrevin protein in Western blots of rat brain lysate.

Kreuzreaktivität (Details): Species reactivity (tested):Human, Pig, Hamster, Rat, Rabbit, Mouse, and Bovine.
Also reacts to: VAMP2

Aufreinigung: Affinity Chromatography.

Immunogen: Synaptic immunoprecipitate (crude) from Human brain.

Isotyp: IgM

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store the antibody undiluted (in aliquots) at -20 °C.

Details zu VAMP1

Target: VAMP1 (Vesicle-Associated Membrane Protein 1 (Synaptobrevin 1) (VAMP1))

Andere Bezeichnung: VAMP-1 / Synaptobrevin-1

Hintergrund: Synaptobrevin (aka VAMP) is an integral membrane protein of synaptic vesicles that plays a major role in the formation of larger SNARE complexes, along with SNAP-25 and syntaxin. Synaptobrevin has been shown to be essential for two fast synapse-specific membrane trafficking processes: fast exocytosis for neurotransmitter release and fast endocytosis that mediates rapid recycling of synaptic vesicles (Deak et al., 2004). Decreased levels of synaptobrevin in human hippocampus and cortex have been correlated with cognitive defects in Alzheimer's disease (Sze et al., 2000).Synonyms: SYB1, VAMP1, Vesicle-associated membrane protein 1

Gen-ID: 6843

NCBI Accession: NP_055046

UniProt: P23763