BCL11A Antikörper (AA 1-89)

Produktnummer ABIN782364

Dieses Anti-BCL11A-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von BCL11A in WB, IHC (p) und EIA. Geeignet für Human.

Kurzübersicht für BCL11A Antikörper (AA 1-89) (ABIN782364)

Target: BCL11A (B-Cell CLL/lymphoma 11A (Zinc Finger Protein) (BCL11A))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser BCL11A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Klon: 3D9

Produktdetails anti-BCL11A Antikörper

Bindungsspezifität: AA 1-89

Spezifität: Recognizes Bcl-11A

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Protein A Chromatography

Immunogen: BCL11A (NP_060484, 1 a.a. ~ 89 a.a) partial recombinant protein with GST tag.

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: PBS, pH 7.2

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid freeze-thaw cycles.

Details zu BCL11A

Target: BCL11A (B-Cell CLL/lymphoma 11A (Zinc Finger Protein) (BCL11A))

Andere Bezeichnung: Bcl-11A

Hintergrund: This gene encodes a C2H2 type zinc-finger protein by its similarity to the mouse Bcl11a/Evi9 protein. The corresponding mouse gene is a common site of retroviral integration in myeloid leukemia, and may function as a leukemia disease gene, in part, through its interaction with BCL6. During hematopoietic cell differentiation, this gene is down-regulated. It is possibly involved in lymphoma pathogenesis since translocations associated with B-cell malignancies also deregulates its expression. Multiple transcript variants encoding several different isoforms have been found for this gene.Synonyms: B-cell CLL/lymphoma 11A, B-cell lymphoma/leukemia 11A, BCL11A, COUP-TF-interacting protein 1, CTIP1, EVI9, Ecotropic viral integration site 9 protein homolog, KIAA1809

Gen-ID: 53335

NCBI Accession: NP_060484

UniProt: Q9H165

Pathways: Regulation of Cell Size