RND3 Antikörper (AA 1-245)

Produktnummer ABIN782334

Dieses Anti-RND3-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von RND3 in WB, IHC (p) und EIA. Geeignet für Human.

Kurzübersicht für RND3 Antikörper (AA 1-245) (ABIN782334)

Target: RND3 (rho Family GTPase 3 (RND3))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser RND3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Klon: 1D2

Produktdetails anti-RND3 Antikörper

Bindungsspezifität: AA 1-245

Spezifität: Recognizes RND3 / ARHE.

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Protein A Chromatography

Immunogen: RND3 antibody was raised against RND3 (AAH12513, 1 a.a. ~ 245 a.a) full-length recombinant protein with GST tag.

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS, pH 7.2

Handhabung: Avoid freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: Store the antibody (in aliquots) at -20 °C or -80 °C.

Details zu RND3

Target: RND3 (rho Family GTPase 3 (RND3))

Andere Bezeichnung: RND3 / ARHE

Hintergrund: Rho-related GTP-binding protein RhoE, also known as RND3, is a small GTPase of the Ras superfamily that regulate the organization of the actin cytoskeleton in response to extracellular growth factors. RND3 activity leads to a decrease in stress fibers and increased cell migration, at least in part through regulation of the Rho-dependent kinase ROCK1. Also, RND3 has been implicated in inhibition of DNA-damage induced apoptosis and cell cycle arrest.Synonyms: MemB protein, RHO8, RHOE, Rho family GTPase 3, Rho-related GTP-binding protein RhoE

Gen-ID: 390

NCBI Accession: NP_005159

UniProt: P61587