SGK1 Antikörper
Kurzübersicht für SGK1 Antikörper (ABIN781842)
Target
Alle SGK1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Spezifität
- This antibody reacts to SGK1.
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Aufreinigung
- Protein A chromatography
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Immunogen
- SGK1 antibody was raised against recombinant protein
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Isotyp
- IgG1
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anti-serum/glucocorticoid Regulated Kinase 1 (SGK1) (AA 1-431) antibody
SGK1 Reaktivität: Human WB, ELISA, IF, IHC (p), RNAi Wirt: Maus Monoclonal 4D7-G3 unconjugated
anti-serum/glucocorticoid Regulated Kinase 1 (SGK1) (pSer422) antibodySGK1 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-serum/glucocorticoid Regulated Kinase 1 (SGK1) (AA 172-431) antibodySGK1 Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-serum/glucocorticoid Regulated Kinase 1 (SGK1) (AA 1-90) antibodySGK1 Reaktivität: Human WB, ELISA, IF, IHC (p) Wirt: Maus Monoclonal 3G8 unconjugated
anti-serum/glucocorticoid Regulated Kinase 1 (SGK1) (AA 145-386) antibodySGK1 Reaktivität: Maus WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-serum/glucocorticoid Regulated Kinase 1 (SGK1) (AA 1-90) antibodySGK1 Reaktivität: Human WB, ELISA, IF, IHC (p) Wirt: Maus Monoclonal 3E3 unconjugated
anti-serum/glucocorticoid Regulated Kinase 1 (SGK1) (pSer78) antibodySGK1 Reaktivität: Human, Maus, Ratte WB, ELISA, FACS, IHC (p), IF (p), IF (cc), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-serum/glucocorticoid Regulated Kinase 1 (SGK1) (AA 247-406) antibodySGK1 Reaktivität: Human WB, ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-serum/glucocorticoid Regulated Kinase 1 (SGK1) (C-Term) antibodySGK1 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-serum/glucocorticoid Regulated Kinase 1 (SGK1) (pThr256) antibodySGK1 Reaktivität: Human, Maus WB, ELISA, FACS, IHC (p), IF (p), IF (cc), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 0,49 mg/mL
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Buffer
- PBS, pH 7.2
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- SGK1 (serum/glucocorticoid Regulated Kinase 1 (SGK1))
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Andere Bezeichnung
- SGK1 / SGK
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Hintergrund
- SGK, a SGK type protein kinase, is a multi-functional kinase that is phosphorylated and activated through a 3-phosphoinositide-dependent protein kinase 1 (PDK1) signaling pathway. The protein has been shown to activate certain potassium, sodium and chloride channels which function in cell survival, neuronal excitability and renal sodium excretion. SGK transcription can be stimulated by glucocorticoids, aldosterone, TGF-beta1, serum, increase of intracellular Ca2+ and phorbolesters, and can be downregulated by cAMP. At least 2 mRNA variants have been reported. The SGK1 gene has been mapped to chromosome 6q23, a region frequently affected by deletion in various human neoplasms, and has been shown to be upregulated in lung fibrosis, diabetic nephropathy and chronic viral hepatitis.Synonyms: Serine/threonine-protein kinase Sgk1, Serum/glucocorticoid-regulated kinase 1
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Gen-ID
- 6446
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NCBI Accession
- NP_001137148
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UniProt
- O00141
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Pathways
- MAPK Signalweg, Notch Signalweg, Steroid Hormone Mediated Signaling Pathway
Target
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