CR1L Antikörper

Produktnummer ABIN781721

Produktdetails anti-CR1L Antikörper

Target: CR1L (Complement Component (3b/4b) Receptor 1-Like (CR1L))

Reaktivität: Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CR1L Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Frozen Sections) (IHC (fro)), Flow Cytometry (FACS)

Spezifität: This antibody detects Crry. The antigen is found on numerous cells in blood and various tissues.

Kreuzreaktivität (Details): Species reactivity (tested):Rat

Aufreinigung: Affinity chromatography

Immunogen: Erythrocytes from a C3 mutated rat

Klon: 512

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Reconstitute by adding 0.5 mL distilled water.

Buffer: Stock solution contains 0.4 mg/mL IgG, phosphate buffered saline pH 7.2 (PBS), 5 mg/mL bovine serum albumin (BSA) as a stabilizer and 0.09 % sodium azide as a preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Prior to reconstitution store at 2-8 °C. Following reconstitution store (in aliquots) at -20 °C.

Details zu CR1L

Target: CR1L (Complement Component (3b/4b) Receptor 1-Like (CR1L))

Andere Bezeichnung: CR1L / CRRY (CR1L Produkte)

Synonyme: CREG antikoerper, Cr1 antikoerper, Crry antikoerper, Mcp antikoerper, mCRY antikoerper, complement C3b/C4b receptor 1 like antikoerper, complement component (3b/4b) receptor 1-like antikoerper, CR1L antikoerper, Cr1l antikoerper

Hintergrund: Crry is a cofactor for complement factor I. Crry seems to act as a costimulatory factor for T-cells and is expressed on different tissues, particularly also on thymocytes and non-lymphoid cells in the thymus. Crry may play an important role in the early embryonic development by maintaining fetomaternal tolerance. Two forms of Crry exist, containing six or seven extracellular short consensus repeats (SCRs), respectively, plus a transmembrane and a cytoplasmic domain. The molecular weights of the native glycoproteins are approximately 55 and 65 kDa, respectively.Synonyms: Antigen 5I2, Complement component receptor 1-like protein, Complement regulatory protein Crry

Gen-ID: 54243

NCBI Accession: NP_001005265

UniProt: Q63135

Pathways: Komplementsystem