GRP78 Antikörper
Kurzübersicht für GRP78 Antikörper (ABIN781236)
Target
Alle GRP78 (HSPA5) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Spezifität
- E ndoplasmic reticulum
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Aufreinigung
- Protein G-Sepharose affinity purified.
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Immunogen
- Recombinant fragment of Human HSPA5 (C-terminus).
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Applikationshinweise
- Recommended dilutions. ELISA: 1/5000 - 1/20000. WB: 1/100-1/2000.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 50µg/50µl
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Buffer
- 0.02% Sodium Azide and 50% glycerol, 1% BSA, PBS, pH7.4.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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- GRP78 (HSPA5) (Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) (HSPA5))
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Andere Bezeichnung
- HSPA5
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Hintergrund
- The 78 kDa glucose regulated protein/BiP (GRP78) belongs to the family of ~70 kDa heat shock proteins (HSP 70). GRP78 is a resident protein of the endoplasmic reticulum (ER) and may associate transiently with a variety of newly synthesized secretory and membrane proteins or permanently with mutant or defective proteins that are incorrectly folded, thus preventing their export from the ER lumen. GRP78 is a highly conserved protein that is essential for cell viability.
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Molekulargewicht
- 48kDa
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NCBI Accession
- NM_005354
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Pathways
- Thyroid Hormone Synthesis, ER-Nucleus Signaling
Target
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