Leptin Receptor Antikörper
Kurzübersicht für Leptin Receptor Antikörper (ABIN781204)
Target
Alle Leptin Receptor (LEPR) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Spezifität
- Plasma membrane
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Aufreinigung
- Protein G-Sepharose affinity purified.
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Immunogen
- Recombinant fragment of Human LEPR (N-terminus).
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Isotyp
- IgG
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Applikationshinweise
- Recommended dilutions. ELISA: 1/5000 - 1/20000. WB: 1/100-1/2000.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 50µg/50µl
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Buffer
- 0.02% Sodium Azide and 50% glycerol, 1% BSA ,PBS, pH7.4.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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- Leptin Receptor (LEPR)
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Andere Bezeichnung
- LEPR
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Hintergrund
- Leptin receptor (LEPR, OB-R) is a type I cytokine receptor family protein with significant amino acid sequence identity with gp130, G-CSF receptor, and LIF receptor. The transcript was reported to be expressed predominantly in regions of the hypothalamus previously thought to be important in body weight regulation. OB-R binds leptin with high affinity and is a potent leptin antagonist.
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Molekulargewicht
- 120kDa
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NCBI Accession
- NM_002303
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Pathways
- JAK-STAT Signalweg, AMPK Signaling, Feeding Behaviour
Target
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