SOCS3 Antikörper

Produktnummer ABIN781166

Dieser Maus Monoklonal Antikörper detektiert spezifisch SOCS3 in WB und ELISA. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für SOCS3 Antikörper (ABIN781166)

Target: SOCS3 (Suppressor of Cytokine Signaling 3 (SOCS3))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser SOCS3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-SOCS3 Antikörper

Aufreinigung: Protein G-Sepharose affinity purified.

Immunogen: Recombinant fragment of Human SOCS3 (N-terminus).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilutions. ELISA: 1/5000 - 1/20000. WB: 1/100-1/2000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 50µg/50µl

Buffer: 0.02% Sodium Azide and 50% glycerol, 1% BSA, PBS, pH7.4.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Details zu SOCS3

Target: SOCS3 (Suppressor of Cytokine Signaling 3 (SOCS3))

Andere Bezeichnung: SOCS3

Hintergrund: SOCS3 is an SH2-containing protein that binds to the activation loop of Janus kinases, inhibiting kinase activity and thereby suppressing cytokine signaling. It is a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. The expression of the SOCS3 gene is induced by various cytokines, including IL6, IL10, and interferon (IFN)-gamma. Studies of the mouse counterpart of the SOCS3 gene suggested this gene is involved in the negative regulation of fetal liver hematopoiesis, and placental development.

Molekulargewicht: 45kDa

NCBI Accession: NM_003955

Pathways: JAK-STAT Signalweg, Response to Growth Hormone Stimulus, Hepatitis C