Vitamin D Receptor Antikörper (AA 150-250)

Produktnummer ABIN8125720

Der Maus Monoklonal anti-Vitamin D Receptor Antikörper (Klon AB2465) (ABIN8125720) detektiert spezifisch Vitamin D Receptor in WB, ELISA und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Vitamin D Receptor Antikörper (AA 150-250) (ABIN8125720)

Target: Vitamin D Receptor (VDR)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Vitamin D Receptor Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Klon: AB2465

Produktdetails anti-Vitamin D Receptor Antikörper

Bindungsspezifität: AA 150-250

Verwendungszweck: Vitamin D Receptor mouse mAb

Spezifität: This antibody detects endogenous levels of Vitamin D Receptor protein.

Aufreinigung: The antibody was purified by protein G affinity chromatography.

Immunogen: A synthetic peptide corresponding to the amino acid region 150 - 250 of the human Vitamin D Receptor protein.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB, 1:500-1:2000 | IF, 1:100-1:500 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze / thaw cycles

Lagerung: -20 °C

Informationen zur Lagerung: Store at-20°C. Avoid freeze / thaw cycles.

Details zu Vitamin D Receptor

Target: Vitamin D Receptor (VDR)

Andere Bezeichnung: Vitamin D Receptor

Substanzklasse: Chemical

Hintergrund:

Synonyms: Vitamin D3 receptor, VDR, 1, 25-dihydroxyvitamin D3 receptor, Nuclear receptor subfamily 1 group I member 1, NR1I1

Background: vitamin D (1, 25-dihydroxyvitamin D3) receptor (VDR) Homo sapiens This gene encodes the nuclear hormone receptor for vitamin D3. This receptor also functions as a receptor for the secondary bile acid lithocholic acid. The receptor belongs to the family of trans-acting transcriptional regulatory factors and shows sequence similarity to the steroid and thyroid hormone receptors. Downstream targets of this nuclear hormone receptor are principally involved in mineral metabolism though the receptor regulates a variety of other metabolic pathways, such as those involved in the immune response and cancer. Mutations in this gene are associated with type II vitamin D-resistant rickets. A single nucleotide polymorphism in the initiation codon results in an alternate translation start site three codons downstream. Alternative splicing results in multiple transcript variants encoding different proteins. [provided by RefSeq, Feb 2011],

Gene Name: VDR

Protein Name: Vitamin D Receptor

Gen-ID: 7421

UniProt: P11473

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway